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Lymphoscintigraphy and radioguided sentinel node biopsy in oral cavity squamous cell carcinoma: same day protocol

The routine use of a sentinel node biopsy (SNB) protocol in oral cavity squamous cell carcinomas (SCC) has been challenged on the basis of the elevated number of sentinel nodes (SNs) detected (>2.5) and on the multiply neck level involvement reported in several studies. These data limit the practical application of the protocol, because in such cases, it seems easierand safer to perform a selective neck dissection. (altro…)

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Sentinel European Node Trial (SENT): 3-year results of sentinel node biopsy in oral cancer

1. Introduction Head and neck squamous cell carcinoma is the eighth most common cancer worldwide in males and is increasing significantly amongst females [1] Approximately half the patients with oral cancer present with stage I/II disease and up to 33% [2,3] have occult cervical disease undetectable by current imaging techniques (computed tomography [CT]/magnetic resonance imaging [MRI]/ultrasound/positron-emission tomography)[4,5]. (altro…)

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